Tracking Transcriptional Evolution Using Circulating Tumour DNA

Unravelling mutational signatures with plasma circulating tumour DNA

S Hollizeck, N Wang, SQ Wong, C Litchfield, J Guinto, S Ftouni, R Rebello, S Kanwal, R Dong, S Grimmond, S Sandhu, L Mileshkin, RW Tothill, D Chandrananda, SJ Dawson

2024-12-01

The use of circulating tumour DNA (ctDNA) to profile mutational signatures represents a non-invasive opportunity for understanding..

The landscape of cell-free mitochondrial DNA in liquid biopsy for cancer detection

Ymke van der Pol, Norbert Moldovan, Jip Ramaker, Sanne Bootsma, Kristiaan J Lenos, Louis Vermeulen, Shahneen Sandhu, Idris Bahce, D Michiel Pegtel, Stephen Q Wong, Sarah-Jane Dawson, Dineika Chandrananda, Florent Mouliere

2023-10-12

Background: Existing methods to detect tumor signal in liquid biopsy have focused on the analysis of nuclear cell-free DNA (cfDNA)..